Research Interests

I am interested in adaptive evolution of organisms above species level. With the affordable price for sequencing and explosive increasing amount of genomic data, we can have a deeper insight into it in context of genomes.
Recently, I am developing algorithm to detect the genetic signal of nature selection from genomes with a brand new method based on evolutionary probability(EP). Current methods (e.g. PAML, HYPHY) for genome-wide selection analysis is vulnerable for missing data, population sampling error, genetic drift, recombination and restriction on CDS data. A brand new method based on evolutionary probability is initially developed by Liu et al. 2015, which is not suffered from problems mentioned above, while population data is still needed for selection detection.
My aim is to develop a method based on EP to detect selection with individual data only. Meanwhile, I am also working on several basic analytical methods for exon capture data including assembling and post-processing pipeline and detecting cross-contaminated samples.